Ibuprofen may temporarily reduce male fertility

10 January, 2018, 01:44 | Author: Earnest Huff
  • Ibuprofen Might Cause Male Infertility Study Shows			 0					By		Denis Bedoya

Some took 1,200 milligrams of ibuprofen daily, which is the maximum limit as directed, over a six-week period. And now, new research shows that it can cause infertility, erectile dysfunction, muscle atrophy and fatigue in men.

Advil and Motrin are two brand names for ibuprofen.

The researchers found that prolonged ibuprofen use suppressed "important aspects of testicular function, including testosterone production".

The other 17 men in the study took a placebo.

The widely-used over-the-counter painkiller ibuprofen may pose a threat to male fertility, suggests a small new study.

However, despite the change in LH levels, the men's testosterone levels didn't change.

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The study, published this week in the journal Proceedings of the National Academy of Sciences (PNAS), monitored 31 healthy white men aged 18 to 35.

For short-term ibuprofen use the effects of compensated hypogonadism are reversible, however the researchers state how it is unknown whether these effects are reversible for long-term ibuprofen use. Before he stepped down in November 2016 he asked players about their use of over-the-counter painkillers and found that almost half of those who played in the past three World Cups took anti-inflammatory drugs, such as ibuprofen, every day.

"The effects were very mild even after six weeks of regular consumption of ibuprofen, which is longer than is usually recommended in practice, so this data should not concern men who occasionally take ibuprofen for pain relief", Ali Abbara, Imperial College London's senior clinical lecturer in endocrinology, told Forbes.

So researchers wanted to look into what happened in adult males who took ibuprofen, which had the strongest results in the earlier study.

The Consumer Healthcare Products Association, a trade group representing the manufacturers of over-the-counter medications, said it was in support of such research and efforts made to educate consumers. This is because the pituitary gland at the base of the brain had ramped up levels of another hormone that drives the production of extra testosterone. Research released in February 2017 also found that it could increase the risk of heart attacks.



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