The much-changed Rams held their own for most of the opening 20 minutes, despite some fine play from Paul Pogba and Juan Mata in the United midfield.
Manchester United (4-3-3): Romero; Lindelof, Jones, Rojo, Blind; Herrera, Matic, Pogba; Lingard, Rashford, Mata.
Jesse Lingard again came up with the goods and Romelu Lukaku was also on target as Manchester United left it late to seal a 2-0 FA Cup third-round win over Derby County. Derby also created a scare as Martin Olsson rose higher to head Alex Pearce's corner but Sergio Romero tipped the goal bound header over the bar. But the team kept trying so I knew the goal could arrive.
United had been frustrated earlier in the game, striking the post on a number of occasions and forcing Scott Carson in to making a number of saves.
Lukaku came off the United bench at the interval as Mourinho looked for more cutting edge in the final third of the field.
Season's worst fog at IGI, over 200 flights hit
The day's average air quality index (AQI) was at 400, classified as "very poor" by the Central Pollution Control Board (CPCB). Dense fog engulfed the national capital region on New Year on Monday with the visibility dropping to zero.
Pogba then curled one wide of Carson's post moments later as both teams had opportunities after the restart.
Derby have injury concerns heading into match as Tom Lawrence, Joe Ledley and Bradley Johnson are all major doubts.
Tom Lawrence almost sent Derby ahead two minutes before the hour with a thumping shot from just outside the box but Sergio Romero made a brilliant save at the bottom corner.
Lingard effectively won it for United in the 84th minute, however, when the Englishman netted his eighth goal in his last 10 appearances - finding the top corner from distance - to break Derby's hearts in the latter stages.
Not to be outdone, Lukaku then played a good give-and-go with Anthony Martial before tucking his shot under the advancing Carson to secure United's passage to the FA Cup fourth round.
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